Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity associated with bortezomib, a proteasome inhibitor Utilized in the remedy of multiple myeloma. Its synthesis or research is crucial for making sure the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Utilized in the therapy of prostate most cancers by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound during the synthesis of imatinib, a drug that targets unique kinds of most cancers, such as Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their examine is very important for optimizing the output approach and ensuring large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is applied to take care of breast cancer, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the therapy of breast most cancers. Numerous intermediates help in the 7-dihydro-4-oxo-1H-pymol[2 synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug powerful in managing cancers like ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment of colorectal cancer and modest mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, that have various applications, like antiviral Houses.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for type 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar amounts.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved in the synthesis of varied b-D-Ribofuranose gluconic acid derivatives, which are used in meals, pharmaceutical, and industrial programs.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication made use of to deal with sort 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).